Benzeneacetonitrile, 2-chloro-5-fluoro-

Benzeneacetonitrile, 2-chloro-5-fluoro- - Names and Identifiers

Name	(2-chloro-5-fluorophenyl)acetonitrile
Synonyms	NC1R BG EF 2-Chloro-5-fluorobenzylcyanide 2-CHLORO-5-FLUOROBENZYL CYANIDE 2-Chloro-5-fluorophenylacetonitrile 2-CHLORO-5-FLUOROPHENYLACETONITRILE (2-Chloro-5-fluorophenyl)acetonitrile (2-chloro-5-fluorophenyl)acetonitrile Benzeneacetonitrile, 2-chloro-5-fluoro- benzeneacetonitrile, 2-chloro-5-fluoro- 2-(2-chloro-5-fluorophenyl)acetonitrile
CAS	395675-23-7
InChI	InChI=1/C8H5ClFN/c9-8-2-1-7(10)5-6(8)3-4-11/h1-2,5H,3H2

Benzeneacetonitrile, 2-chloro-5-fluoro- - Physico-chemical Properties

Molecular Formula	C8H5ClFN
Molar Mass	169.58
Density	1.286g/cm³
Melting Point	58-59°C
Boling Point	249.8°C at 760 mmHg
Flash Point	104.9°C
Vapor Presure	0.0225mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.528

Benzeneacetonitrile, 2-chloro-5-fluoro- - Risk and Safety

Hazard Symbols	Xi - Irritant
Hazard Class	IRRITANT, IRRITANT-H

Benzeneacetonitrile, 2-chloro-5-fluoro- - Introduction

(2-chloro-5-fluorophenyl)acetonitrile is an organic compound with the chemical formula C8H4ClFN. It is a solid, common properties include a colorless to pale yellow crystalline solid, soluble in organic solvents such as chloroform, dimethylformamide and ethanol.

(2-chloro-5-fluorophenyl)acetonitrile are often used in organic synthesis reactions in the laboratory, especially for the synthesis of other organic compounds. It can be used as an intermediate in drug synthesis and for the preparation of other important organic synthetic materials.

About the preparation method, a commonly used method is to react p-nitrotoluene with chloroacetonitrile, and obtain the target product through a multi-step reaction. The intermediate steps include hydrogenation, substitution and other reaction processes.

Pay attention to safety when using and handling (2-chloro-5-fluorophenyl)acetonitrile. It is an organic compound with certain toxicity. Wear personal protective equipment such as protective gloves, goggles and protective clothing during operation. Avoid contact with skin, eyes and respiratory tract. Avoid inhaling gas or dust and maintain a well-ventilated operating environment. Disposal of waste in accordance with local regulations. In the event of an accident, medical help should be sought immediately.

Last Update：2024-04-09 21:54:55